Long-term outcomes of hysterectomy with bilateral salpingo-oophorectomy: a systematic review and meta-analysis

https://www.sciencedirect.com/science/article/pii/S0002937823004416?utm_campaign=STMJ_AUTH_SERV_PUBLISHED&utm_medium=email&utm_acid=101158843&SIS_ID=&dgcid=STMJ_AUTH_SERV_PUBLISHED&CMX_ID=&utm_in=DM385143&utm_source=AC_

What does this add to what is known?

Our findings show that hysterectomy with BSO at any age reduces the risk of ovarian cancer and that hysterectomy with BSO at a young age is associated with a reduced risk of breast cancer. Nevertheless, this risk reduction should be balanced against the possible increase in the risk of CVD, colorectal cancer, and all-cause mortality in young women. Furthermore, more evidences on the efficacy of hormone replacement therapy in mitigating the adverse effects of the premature cessation of estrogen are needed.

Conclusion:

Hysterectomy with bilateral salpingo-oophorectomy was associated with multiple long-term outcomes. The benefits of the addition of bilateral salpingo-oophorectomy to hysterectomy should be balanced against the risks.