Is the process of informing family members of a genetic condition discovered within the family, followed by family members getting tested for the condition.
It can identify who inherited the mutation and who did not. This will allow those who have inherited the mutation to take steps to reduce the risk of cancer. Genetic testing saves lives.
Cascade Testing is one of the most important steps in breaking the cycle of hereditary cancer in families. This testing-sharing-testing-sharing of genetic information plays a vital role in protecting the health and lives of loved ones in families with a history of cancer.
It requires a number of important steps:
1. Having testing done. 2. Sharing that information, which includes test results and the specific mutation in the gene.
In Lynch syndrome mutations in the following genes may increase the risk of cancer: MLH1, MSH2, MSH6, PMS2 and ЕРСАМ.
Lynch Syndrome Ireland 