Most people with Lynch syndrome are well, but someone with LS has a 40-70% chance of developing colon cancer, and women also have a similar risk of cancer of the womb. All those with LS have an increased risk of many other types of cancer. The genetic mutations which cause Lynch Syndrome can be passed on from one generation to the next, with a 50% risk of a child inheriting this condition.
The programme has four main aims:
1) Effective diagnosis and identification of people with LS in the UK
2) Improve understanding of the biological mechanism of cancer development of people with LS
3) Develop additional tests which facilitate the prevention and early diagnosis of cancer in people with LS
4) Reduction in the variation of – and improvement in access to – care for people with LS in the UK