Risk-stratified faecal immunochemical testing (FIT) for urgent colonoscopy in Lynch syndrome during the COVID-19 pandemic

Lynch syndrome is a hereditary cancer disease resulting in an increased risk of colorectal cancer. Findings are reported from an emergency clinical service implemented during the COVID-19 pandemic utilising faecal immunochemical testing (‘FIT’) in Lynch syndrome patients to prioritise colonoscopy while endoscopy services were limited.

Fifteen centres participated from June 2020 to March 2021. Uptake was 68.8 per cent amongst 558 patients invited.

Conclusion

FIT demonstrated clinical value for Lynch syndrome patients requiring colorectal cancer surveillance …. Further longitudinal investigation on FIT efficacy in Lynch syndrome is warranted and will be examined under the ‘FIT for Lynch’ study (ISRCTN15740250).

https://academic.oup.com/bjsopen/article/7/5/zrad079/7260320?login=false

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