VUS-

Variant of Uncertain Significance is a genetic test result indicating a change in your DNA, but scientists currently lack enough data to know if it is harmless or causes disease.

Determining whether a genomic variant is truly disease-causing is a rigorous scientific process.

“It requires robust evidence, internationally agreed standards, and often detailed discussion within multidisciplinary teams of clinicians, laboratory scientists, bioinformaticians, and genetic counsellors. Variants are not simply “found” and reported; they are carefully evaluated, challenged, and reviewed before any meaningful conclusions can be drawn.”