The Cancer Moonshot℠ Blue Ribbon Panel Report, published in October 2016, identified clinical and research opportunities to expand use of proven cancer prevention and early detection strategies to improve patient outcomes and has recommended projects related to cancer genetic testing (Recommendation G).
Provides comprehensive clinical guidance that can be referenced by both patients and clinicians so that women with Lynch syndrome can expect and receive appropriate standards of care.
“Our key recommendations are as follows: The Manchester International Consensus Group recommendations for the management of gynecologicalcancers in Lynch syndrome:
(1) all stakeholders should be informed of the impact of Lynch syndrome on gynecological cancer risk;
(2) systems should be established to screen for Lynch syndrome in women with endometrial cancer;
(3) women at risk of Lynch syndrome should be offered risk-reducing hysterectomy with bilateral salpingo-oophorectomy, at a time appropriate to them; and
(4) further research is required to establish the value ofgynecological cancer surveillance in Lynch syndrome and toexplore other key areas where there is currently deficientevidence to define appropriate standards of care.
Screening for Lynch syndrome is only recommended if effective management exists to benefit those who screen positive.The strength of our guidance comes from the broad andexpert medical specialty representation that forms ourConsensus Group.”
Philomena is a 2013 British-French drama film directed by Stephen Frears, based on the 2009 book The Lost Child of Philomena Lee by journalist Martin Sixsmith…….
I stood at the same door and spoke to the same Nun in 1994(the year I met my 47 y.o. sister for the first time).
In time this discovery led to learning I had inherited the MSH2 gene mutation and Lynch Syndrome affected my family.
Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from
the Prospective Lynch Syndrome Database.
“You exist in a kind of limbo, trapped between your old life and an almost inevitable early death. There’s only one way out, the only question is when?”