For decades, genetic testing was rationed, reserved only for patients who fit narrow, outdated clinical guidelines. But what happens when those guidelines leave countless people at risk?
In this episode, clinical geneticist and medical innovator Dr. Ed Esplin of LabCorp Genetics reveals how his team’s groundbreaking research exposed the flaws in restrictive testing policies. Through rigorous studies in breast cancer, colorectal cancer, and beyond, they proved that universal germline genetic testing identifies far more at-risk patients than guidelines ever predicted and fundamentally changes how we treat and prevent disease.
The data has forced a reckoning: when up to “50% of high-risk patients were being missed”, “standard of care” was anything but standard care.
From community oncology clinics to rare disease diagnostics, he makes the case that access to genetic insights should be driven by evidence, not just eligibility criteria.
Lynch Syndrome Ireland 