Can Lifestyle Alter Genetic Risk? What the science says.

Lynch syndrome confers an inherited genetic predisposition — but environmental and lifestyle factors also influence how that risk is expressed. 

Current evidence indicates that chronic inflammation may contribute to tumour development in mismatch repair-deficient cells. Modifiable factors — including regular physical activity, avoiding tobacco, and a diet high in fibre and low in processed meat — may therefore support risk reduction.

These measures complement, but do not replace, established clinical surveillance.

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