Author: Lynch Syndrome Ireland

Early detection of cancer

Early detection of cancer makes treatment more likely to be successful.

Here’s a reminder of some of the most common signs & symptoms. Remember, these signs can be linked to other conditions too, but it’s important to talk to your GP if they persist for 3 weeks or more

https://x.com/BreakthroCancer/status/1702698796801556671?s=20

Consumer genetic test results ‘causing unnecessary breast cancer alarm’

Consumer genetic test results ‘causing unnecessary breast cancer alarm’… this is why pre- and post-test counselling is crucial!

This latest study suggests that the risk carried by BRCA variants depends on secondary genetic factors, meaning family history is crucial for understanding an individual’s risk.

https://www.theguardian.com/society/2023/sep/15/consumer-genetic-test-results-causing-unnecessary-breast-cancer-alarm?CMP=Share_iOSApp_Other

European Hereditary Tumour Group(EHTG)

EHTG has a track record of expanding guidelines and practises the concept of “dynamic guidelines”. This concept means that whenever evidence has been produced in the published literature that should lead to a change of previous guidelines and is relevant for the clinical management of a syndrome, EHTG will ask for a revision of the corresponding chapter. 

Welcome everybody interested to get actively involved and join them in these efforts to improving our knowledge in the field of hereditary predisposition to cancer and to implement this knowledge for improved clinical care. This effort embraces all clinical disciplines!

https://www.ehtg.org/guidelines.php

#GOforTesting #GOforPrevention

What do negative results from a genetic test mean?

Sounds like good news. Negative test results means that the laboratory didn’t find any mutations in one´s 🧬 DNA that are known to increase the risk of developing cancer.

☝️ But don’t forget! It is still necessary to undergo regular check-ups and take care of your health every day.

Unlocking the Potential of Patient Registries: A Guide for Success

Patient registries play a crucial role in enhancing healthcare and health outcomes, serving as vital foundations for developing and maintaining research networks and projects. 
Unlocking the Potential of Patient Registries: A Guide for Success

The Big Prostate Quiz

Stand Up for Your Prostate and take the Big Prostate Quiz this Blue September to check if you need to be more aware of your prostate health. It will take less than 5 minutes to take the Quiz, about the same time it takes to get your PSA Checked!

We are asking the men of Ireland to once again to Stand Up for Your Prostate.
Get your PSA checked once you reach the age of 50 or at 45 if you have a family history of Prostate or Breast Cancer. It could save your life.
https://mariekeating.ie/thebigquiz/?_cldee=5tKeNl765nzyVBktkm61vOgNUNlyBwZn5x7KwzCUT61cMg1Kkwcde04tabh2jT8u&recipientid=contact-f0234cb799e5e811816170106fa7b0a1-3638ca5ac4d147e6a8d217f9dc152341&esid=d5915bb6-3c4e-ee11-be6f-6045bd86f37b

Does Colon Cancer run in YOUR Family?

The genetic risk for colon and rectal cancer.

  • The risk of developing colorectal cancer increases 2-3 times when a parent, sibling, or child is diagnosed compared to those with no family history.
  • The risk increases 3-6 times over the general population, when a relative is diagnosed at a young age or if there is more than one relative with colorectal cancer.
  • About 20% of all colorectal cancer patients have a close relative who was also diagnosed with the disease.
  • About 5% of patients with colorectal cancer have a well-defined genetic syndrome that causes the disease like Lynch syndrome or familial adenomatous polyposis (FAP).  These conditions are linked with higher risks for colon and other cancers.
  • Lynch syndrome accounts for 2- 4% of all colorectal cancer cases.
  • FAP is the second most common predisposing genetic syndrome; for these individuals, lifetime risk of colorectal cancer approaches 100% without intervention.
Genetics