Womb Cancer Genomics – Research and Patient Benefit

Peaches Womb Cancer Trust is proud to present part one of their womb cancer genomics webinar. Originally aired in November 2022.

With Dr Neil Ryan, who shares his wealth of expertise in Lynch Syndrome.

Note: Can be viewed on You Tube

For more information on the topics discussed, please visit:

https://peachestrust.org/

https://peachestrust.org/peaches-pati…

https://www.lynch-syndrome-uk.org/

https://www.genomicsengland.co.uk/

How to be a Patient. It’s ok to make a fuss.

https://www.irishtimes.com/health/2023/01/22/how-to-be-a-patient-its-okay-to-make-a-fuss-about-yourself/

Kirstie Alley’s Cause Of Death Explained

Kirstie Alley, best known for her Emmy award-winning role as Rebecca Howe on “Cheers,” died Monday night of colon cancer (via People). She was 71.

Her children, True and Lillie Parker, said in a statement on Twitter that her cancer diagnosis was “recently discovered” and that her closest family members were with her. She was receiving treatment at the Moffitt Cancer Center.

Read More: https://www.healthdigest.com/1128029/kirstie-alleys-cause-of-death-explained/?utm_campaign=clip

According to the American Cancer Society, colon cancer might not have symptoms at first, and one could be symptom-free before finding out the cancer has spread.

For those with a genetic predisposition, like Lynch Syndrome, it can spread faster and occur at younger ages (per Fight Colorectal Cancer). Doctors recommend regular colon cancer screenings at age of 45 for anyone with an average risk and even younger for those with a genetic risk factor.

Read More: https://www.healthdigest.com/1128029/kirstie-alleys-cause-of-death-explained/?utm_campaign=clip

Johanne’s story

Genetic testing “it can only help you if you are armed with more information…”

https://www.dropbox.com/s/3b5vrkyqzwbzcxl/JOANNE%20SLATTERY%20FINAL.mp4?dl=0

National Cancer Registry Ireland Annual statistical report 2022

One notable milestone we report this year is that, by the end of 2020, for the first time, the number of people living after an invasive cancer diagnosis had exceeded the 200,000 mark to reach 207,000. This is equivalent to 4.2% of the population, or about 1 in 24 persons in Ireland, a >50% increase in numbers of cancer survivors compared with one decade ago. This reflects both an increase in the number of people being diagnosed with cancer every year and ongoing improvements in cancer survival, as also reported here.

https://www.ncri.ie/sites/ncri/files/pubs/NCRI_AnnualStatisticalReport_2022.pdf?fbclid=IwAR202xw_0A0MbdJ08ygDH7I_t_t4Ziru6za4Pt0DpAPWGMEZjRNTjZsq5Wc

FIT for Lynch Study

This research study is currently being offered in
several NHS Trusts within England and Scotland.

Contact: fitforlynchstudy@kcl.ac.uk

I have a VUS (Variant of Uncertain Significance) Now what?

When you agree to genetic testing, you expect a yes or no answer:  yes, you have an abnormal change in a gene that increases your cancer risk, or no, you don’t. But sometimes, you might not get a clear “yes” or “no.” You might just get a “maybe.”

Are genetic variants of uncertain significance common?

Almost 20% of genetic tests identify a VUS. These tests come in different “sizes.” Some examine only a handful of genes associated with cancer at a time, while others analyze up to 80 genes. The more genes you look at, the more variants of uncertain significance you’ll find.

https://www.mdanderson.org/prevention-screening/family-history/genetic-testing.html

Lynch Syndrome- St Marks

Patient Information – 2019

  1. What is the chance of developing cancer if a faulty gene is found? Not everyone who carries a Lynch syndrome pathogenic variant will develop cancer. The risk of developing cancer is considerably lower in those who know they have Lynch Syndrome compared to those who have it but are unaware of the diagnosis.