| Coding DNA | Noncoding DNA |
| They have a DNA sequence to encode for proteins. | These DNA sequences do not encode for protein. |
| The coding sequence has exons. | It has regulatory elements, introns, repeating sequences, pseudogenes, and telomeres. |
| They are approximately 1% of our total genome. | They form around 99% of our genome. |
| They encode proteins that have regulatory, structural, as well as functional importance. | They control and regulate gene activity. |
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I have also learnt along the way that people have very different opinions about how to do research, what is important and not, and how you should spend your time at work and outside the working hours. My advice is to find your inner voice and stay faithful to your values and goals. Listen and learn by your colleagues, friends and family, but don’t let others decide what is right for you
Matt Cooper the Last word. Miriam Staunton Talks about UCAN Ireland launch and problems around access to New Drugs. Listen back here
The EU has set a deadline of 2030 for Member States to have EHRs accessible to all citizens.
“This is a big project, certainly €2 billion to €3 billion over 10 years. This is not a small investment. It’s very significant. That’s not just the product. That’s all of the staff, all of the change,” he said. “If we don’t make the investment and take some pain, we won’t get the return at a later point.”
…..About time.
St James’s is the national referral centre for adult inherited cancer genetics. Patients are referred from general practitioners, regional hospitals and cancer centres for cancer genetic counselling, risk assessment, and genetic testing.
The testing provider would be responsible for subcontracting a courier service to track the sending and receipt of genetic testing kits; processing of the sample for cancer genetic testing; bioinformatics and data analysis and result outcome; and confidentiality of information submitted to the online portal to order the test.
As of early 2025, more than 2,600 adults nationally were awaiting a genetics outpatient appointment, with more than 750 waiting more than 18 months.
If you’ve received chemotherapy as part of your colon cancer treatment, one of the side effects you may experience is numbness and tingling in you extremities, also known as peripheral neuropathy.
Numbness and tingling of your extremities (hands and feet) is called peripheral neuropathy. This condition is associated with several causes, including chemotherapy to cancer treatment, and involves damage to the nerves between the extremities and the central nervous system.
Recovery from peripheral neuropathy is usually slow, but steps can be taken to encourage regeneration of the damaged nerves. Some approaches include acupuncture, massage, physical therapy, and transcutaneous nerve stimulation.
https://news.cancerconnect.com/cervical-cancer/colon-cancer-understanding-peripheral-neuropathy
Increasing numbers of younger patients are being diagnosed with late-stage colorectal cancer.
What are the Epidemiological factors behind it, the age groups being affected, symptoms people should be paying attention to, preventative screening options, and where the research is going to try to reverse this alarming trend?
“I know this is an uncomfortable conversation for some, but it’s really important, and if there’s any question about whether polyps were removed and whether they’re the advanced kind or not … take photos to show those to your doctor,” Patel said. “Because patients with a family history of advanced polyps qualify for screening earlier and more frequently.”
https://news.cuanschutz.edu/news-stories/why-are-colorectal-cancer-patients-getting-younger
Research has shown that junior doctors are exposed to significant negative discourse around general practice as a specialty during their hospital-based training. The blaming of GPs for emergency department crowding is almost as inevitable as brand-new Health Ministers blaming consultants for the failings of the entire HSE (brand-new Health Ministers don’t tend to blame GPs for anything; they just forget we exist).
Perhaps we need to change the hashtag to #JustaHuman.
Lynch Syndrome Ireland 