Blog

The art of listening

Lead author Dr Leonard Berry of the University of Texas, US, argues that the art of listening is a potent tool that not only helps the patient and doctor, but also has the potential to positively affect health systems in their entirety.

Effective listening, he explains, is targeted and is about asking the right questions and showing genuine compassion and empathy.

https://www.sciencedaily.com/releases/2025/08/250820000803.htm

Low-dose aspirin can prevent bowel cancer in people with Lynch syndrome

A little dose goes a long way.

CaPP3’s results show that taking as little as 75 to 100mg of aspirin each day can halve the risk of bowel cancer in people with Lynch syndrome, a heritable genetic condition that makes bowel cancer much more likely. The findings mean regulators and doctors should soon be able to recommend a specific low-dose aspirin prescription for people with Lynch syndrome, protecting many more of them from bowel cancer.

https://news.cancerresearchuk.org/2025/06/24/capp3-low-dose-of-aspirin-can-prevent-bowel-cancer-in-people-with-lynch-syndrome/

Lynch Syndrome UK Conference 2025 -Highlights

Below you’ll find short summaries of each talk, with a link to the YouTube recordings on our YouTube channel, as well as links to additional useful resources at the end.

https://www.lynch-syndrome-uk.org/post/lynch-syndrome-conference-2025-highlights

Universal Germline and Tumor Genomic Testing Needed to Win the War Against Cancer: Genomics Is the Diagnosis

Universal germline testing may not only transform the outlook for those with traditional hereditary cancer syndromes but also identify a wider range of associations and penetrance for germline variants.

If we are serious about winning the war against cancer, we need to have every bit of intelligence about it, both to treat cancer and to detect it early. The potential impact of the host should be considered in every patient with cancer.

Applying universal germline testing to patients with cancer routinely is one of the major opportunities that can revolutionise precision medicine practice and is needed to win the war against cancer (and possibly many other diseases).

What About the Cost?

Many arguments against testing are centered around the cost. Yet, the cost of germline testing (and next-generation sequencing in general) has markedly decreased over the past decade. Furthermore, patients get repeat routine prevention testing (mammograms, computed tomography scans for lung cancer, colonoscopies, or laboratory tests), which are quite expensive, compared with one time hereditary testing cost, which may be invaluable for the patient over an entire lifetime and informative for their family.

In addition, the cost of the test must be weighed against the cost of expensive (and possibly futile) therapy the patient will be subjected to because this genetic information was not available in a timely manner.

https://ascopubs.org/doi/10.1200/JCO.22.02833

From smart knives to virtual reality tumours: five innovations in understanding cancer

Using virtual reality (VR) coupled with sophisticated imaging and software technologies, scientists will before long be able to step inside interactive maps of patients’ tumours, looking at them in unprecedented detail, and understand better than ever how the cells interact and behave.
And the immersive experience should also open new opportunities for scientific collaboration. Researchers and physicians anywhere in the world could meet in VR spaces to study tumours in ways that simply aren’t possible in 2D.

https://www.cancerresearchhorizons.com/news-and-events/our-articles/smart-knives-virtual-reality-tumours-five-innovations-understanding-cancer

New Insights Into Metachronous Colorectal Cancer Risk in Lynch Syndrome

Background & Aims

Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome. The choice of extended or partial colectomy in patients with LS with primary CRC may influence the risk of metachronous CRC. This study aimed to identify factors associated with metachronous CRC risk and evaluate their potential implications for surgical decision-making.

Metachronous (CRC) is a new, separate primary cancer of the colorectum that develops after a patient has already been diagnosed with and treated for an initial CRC.

Conclusions:

This study identifies important risk factors for metachronous CRC in patients with LS, which may support personalised counseling regarding surgical strategies. The findings highlight the complexity of surgical decision-making and the need for individualised approaches. Further studies are required to refine risk stratification and evaluate long-term outcomes to optimise patient care.

https://www.cghjournal.org/article/S1542-3565(25)00638-X/fulltext

Does cancer run in my family?

Cancer in your family may be caused by an inherited genetic change if:

  • You have a close (‘first degree’) relative, such as a parent, brother, sister or child, who has been diagnosed with 2 separate cancers. For example, bowel cancer and endometrial (womb) cancer
  • 2 or more close relatives on the same side of your family have had the same cancer
  • You or one of your relatives have a cancer most commonly seen in the opposite sex (for example, male breast cancer)
  • You have Ashkenazi Jewish ancestry
  • You have had cancer at a younger age than commonly seen (for example, bowel cancer under the age of 50)

This list is a guide only. If any of the above points apply to you, it is possible, but not certain, that you have an inherited genetic cause for cancer in your family.

https://www.cancer.ie/cancer-information/about-cancer/cancer-and-genes

https://www2.hse.ie/conditions/lynch-syndrome/

COPING WITH CANCER: SEEING A COUNSELLOR

I never felt like “it” couldn’t happen to me. It’s just genetics. Luck of the draw. It’s how the universe works. Not to make light of things, but in a phrase it is what it is.”

“Neither did I feel the the need for a support group. The last thing I wanted to do when I wasn’t being a cancer patient is be a cancer patient.”

Lynch Syndrome UK – New Website

Check out their newly launched version….lots of information that you might find useful.

https://www.lynch-syndrome-uk.org

The responsibility of health: shifting the focus from individuals to systems

Policy translations that solely place responsibility on individuals can exacerbate inequalities and prove counterproductive.

Shifting the focus to systemic actions can promote environments that foster individual healthy choices. This transformation can only be achieved through measures that acknowledge the boundaries of individual responsibility for health and encourage shared accountability within a wider societal context where social and commercial determinants are addressed.

By focusing on systemic solutions rather than individual blame, we can create a society where health equity is achievable and sustainable for all.

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00013-1/fulltext?dgcid=bluesky_organic_corr25_lanpub