Having a Hereditary Cancer Syndrome Has Changed My Life

“Your diet is not only what you eat. It’s what you watch, what you listen to, what you read and the people you hang around, be mindful of the things you put into your body emotionally, spiritually and physically.”

https://www.curetoday.com/view/having-a-hereditary-cancer-syndrome-has-changed-my-life

September is Gynaecological Cancer Awareness Month

Check out this valuable source of information: https://thisisgo.ie

Targeted immunotherapy helps Florida woman beat Lynch syndrome-driven colon cancer

“Fortunately, there’s been a lot of work for patients with Lynch syndrome,” says Dr. Jones. “It used to be that they had really aggressive cancers, and we just didn’t have a great way of treating them. But over the last five to seven years, we’ve had an explosion of drugs called immunotherapies. We’ve seen dramatic responses and unlikely cures in patients.”

https://cancerblog.mayoclinic.org/2022/07/13/targeted-immunotherapy-helps-florida-woman-beat-lynch-syndrome-driven-colon-cancer/

Lynch syndrome; towards more personalised management?

The lifetime risk of each cancer in people with Lynch syndrome is gene-specific and may be modified by environmental factors.

Furthermore, the benefits of surveillance strategies need to be balanced against the risk of over-diagnosis and be supported by evidence of improved outcomes from cancer diagnosis in surveillance.

Therefore, people with Lynch syndrome may benefit from a personalised management approach.

https://pubmed.ncbi.nlm.nih.gov/35988964/

Resistant Starch Provides Lasting Benefit in Lynch Syndrome

Regular bowel screening and aspirin reduce colorectal cancer among patients with LS but extracolonic cancers are difficult to detect and manage. This study suggests that RS reduces morbidity associated with extracolonic cancers.

Taking a supplement of 30 grams of “resistant starch” a day – about the amount in two slightly unripe bananas – reduced the risk of multiple forms of cancer in people with Lynch Syndrome

https://www.newscientist.com/article/2330638-starch-supplement-reduces-the-risk-of-some-hereditary-cancers/?fbclid=IwAR2NMmNDRsS2FnG6mNQhM8UqGuBlCGld3xAfKtV2hPG6laYP8RkRAqWDTVY

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

Half of all cancer deaths could be avoided by behavioural change. More could be prevented if we identified those at genomic risk and implemented risk reduction strategies. Funders must fund more prevention research. It’s the low hanging fruit

Although some cancer cases are not preventable, governments can work on a population level to support an environment that minimises exposure to known cancer risk factors. Primary prevention, or the prevention of a cancer developing, is a particularly cost-effective strategy,

8although it must be paired with more comprehensive efforts to address cancer burden, including secondary prevention initiatives, such as screening programmes, and ensuring effective capacity to diagnose and treat those with cancer. 

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01438-6/fulltext?dgcid=raven_jbs_etoc_feature_gbd22_lancet#seccestitle160

IMPROVING THE LIVES OF INDIVIDUALS AND FAMILIES FACING HEREDITARY CANCER.

FORCE(USA) has extended their efforts and programs to include the millions of people and families who face breast, ovarian, pancreatic, prostate, colorectal and endometrial cancers as a result of Lynch syndrome, or an inherited mutation. http://ow.ly/NfWX50KjtG1

Germline and Somatic Variants: What Is the Difference?

Cancers caused by germline pathogenic variants are called inherited or hereditary. More than 50 different hereditary cancer syndromes have been identified that can be passed from one generation to the next e.g. Lynch Syndrome

https://voice.ons.org/news-and-views/germline-and-somatic-variants-what-is-the-difference

The stigma around poo really bums us out – help us put an end to it. #Auguts #HaveYouGotTheGuts

“I lost my shame very quickly when my new consultant said “do you mind if I put my finger up your bottom?” and did so in front of several junior doctors. But what good has shame ever done me anyway?

https://fb.watch/eNROxMGMkF/